Monitoring of cerebral high intensity transient signals during catheter interventions and surgery for congenital heart disease in infants using NeoDoppler

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): The Joint Research Committee between St. Olavs Hospital and the faculty Medicine, NTNU. Norwegian Association for Children with Congenital Heart Disease Foundation, FFHB Background There is a risk gaseous- solid micro embolus formation during transcatheter procedures (CATH) surgery in children congenital heart disease (CHD). Silent strokes or CATH may contribute to neurological impairment. NeoDoppler non-invasive ultrasound system based on plane wave transmissions continuously monitor cerebral blood flow infants an open fontanelle. Gaseous- passing through beam create High Intensity Transient Signals (HITS) Doppler signal. Purpose We aimed study amount HITS using NeoDoppler. Methods probe operates at frequency 7.8 MHz. frame rate 300 fps covers wide cylindrical area (10/35mm width/depth). displays color M-mode spectrogram. broad permits prolonged scanning time each event as move beam. high framerate allows tracking embolies depth. In this was attached anterior fontanelle CHD (n = 15) cardiac 13). were defined intensity signal creating skewed lines moving away towards (blue/red) corresponding grouped into single curtain effect. Single effect multiple increase that filled entire doppler curve. are believed represent numerous could not be separated from other manually detected in-house MatLab application. Results group consisted 28 (17 males) different who underwent surgery. median age weight 96 days (range 3-240 days) 5650 g 2400-8085 g). 13/15 patients total 392 (Median 12, Range 0-149) all 772 45, 11-150). picture shows examples (panel A) B). One can appreciate embolic trajectory pattern depth over Display. Conclusion we found enables detection frequent undergoing CATH. become useful tool guide modifications procedures, aim reduce silent stroke. However, further studies needed validate technique. Figure.